In the game, players control Pokémon characters and engage in fast-paced five-on-five battles to earn points and achieve victory. In order to succeed in Pokémon UNITE, players must master a variety of game mechanics, each of which contributes to the game's overall strategy and depth.

At the start of each game, players select a Pokémon character to control from a diverse list of options. Each Pokémon has its own unique abilities, strengths, and weaknesses, allowing players to tailor their choices to their preferred playstyle and team composition.

As players progress through the game, their chosen Pokémon earn experience points by defeating wild Pokémon, enemy Pokémon, and completing objectives. As a Pokémon levels up, it may evolve into a more powerful form, unlocking new abilities and enhancing its attributes. Evolutions can significantly affect a Pokémon's effectiveness in battle and can turn the tide of a match.

Pokémon in UNITE can use a range of moves and abilities in battle. These actions range from offensive attacks to defensive maneuvers and support capabilities. Players must strategically choose which moves to use based on the situation, the role of their Pokémon, and the makeup of the opposing team.

The game takes place on different maps and arenas, each with its own layout, objectives, and dangers. Players must strategically navigate these environments, capture wild Pokémon, defeat opponents, and score points by injecting Aeos energy into goal areas.